Description

1-Chloro-3-Phthalimido-2-Propanone is a specialized organic compound featuring a reactive chloroketone group linked to a phthalimide moiety, making it a valuable bifunctional building block in synthetic chemistry. This compound is engineered to serve as a key intermediate for the synthesis of complex molecules, offering precise control over molecular architecture. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing nitrogen heterocycles or designed for targeted biological activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where its reactive sites allow for the construction of specific bioactive scaffolds.
• Peptidomimetic Research: Serves as a building block for creating peptidomimetics and protease inhibitors, valuable in drug discovery programs for diseases like cancer and viral infections.
• Cross-linking Agent: Its reactive chloroketone group can be utilized in polymer chemistry and material science to create cross-linked networks or functionalize surfaces.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein interactions within biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-Chloro-3-Phthalimido-2-Propanone
CAS No.	35750-02-8
Molecular Formula	C₁₁H₈ClNO₃
Molecular Weight	237.64 g/mol
Synonyms	N-(3-Chloro-2-oxopropyl)phthalimide; 3-Chloro-1-phthalimidopropan-2-one; 1-Chloro-3-phthalimidopropan-2-one; 2-Propanone, 1-chloro-3-phthalimido-; Phthalimide, N-(3-chloro-2-oxopropyl)-; 35750-02-8; 1-Chloro-3-phthalimidoacetone
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-3-Phthalimido-2-Propanone is manufactured under strict quality management protocols. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.