Description

1-Tosyl-6,7-Dihydro-1H-Indole-4(5H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its tosyl-protected indole core structure. This compound is critical for the synthesis of complex bioactive molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds and natural product analogs due to its reactive functional groups.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use in the development of enzyme inhibitors or receptor modulators for biochemical assays.

Basic Information

Product Name	1-Tosyl-6,7-Dihydro-1H-Indole-4(5H)-One
CAS No.	35577-89-0
Molecular Formula	C15H15NO3S
Molecular Weight	289.35 g/mol
Synonyms	1-(4-Methylphenyl)sulfonyl-4,5,6,7-tetrahydro-1H-indol-4-one; 4,5,6,7-Tetrahydro-1-tosyl-1H-indol-4-one; 1-Tosyl-4,5,6,7-tetrahydroindol-4-one; 1-(p-Toluenesulfonyl)-4,5,6,7-tetrahydro-1H-indol-4-one; 4-Oxo-1-tosyl-4,5,6,7-tetrahydro-1H-indole; 1-Tosyl-4-oxo-4,5,6,7-tetrahydro-1H-indole
EINECS	Contact for details

Quality Control

Our 1-Tosyl-6,7-Dihydro-1H-Indole-4(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.