Description

Sodium Borohydride, [3H] is a tritium-labeled derivative of the versatile inorganic reducing agent sodium borohydride. This isotopically labeled compound is essential for precise mechanistic studies and analytical applications where tracking hydrogen transfer is critical. It is primarily utilized by researchers and scientists in pharmaceutical development, organic synthesis, and metabolic research who require high-specific-activity reagents for tracer experiments.

Application

• Mechanistic Studies in Organic Chemistry: Tracing the source and pathway of hydride transfer in reduction reactions.
• Pharmaceutical Research & Development: As a labeled reducing agent in the synthesis of deuterated or tritiated drug candidates and metabolites.
• Analytical Chemistry: Use as a tracer in development and validation of analytical methods, including HPLC and mass spectrometry.
• Biochemical Research: Investigating enzymatic reduction mechanisms and metabolic pathways involving NADPH or similar cofactors.
• Material Science: Studying surface modification and reduction processes where hydrogen incorporation needs to be quantified.
• Radiopharmaceutical Precursor: Potential use in the synthesis of labeled compounds for diagnostic imaging or research.

Basic Information

Product Name	Sodium Borohydride, [3H]
CAS No.	35576-64-8
Molecular Formula	B[3H]4Na or NaB[3H]4
Molecular Weight	Contact for details (varies with specific activity)
Synonyms	Sodium Tetrahydroborate-[3H]; Tritiated Sodium Borohydride; Sodium Borotritiide; NaB[3H]4; Sodium Borohydride-t; Sodium Tetrahydroborate-t; [3H]-Sodium Borohydride; Sodium Borohydride (T)
EINECS	Contact for details

Quality Control

Every batch of Sodium Borohydride, [3H] is produced and handled under stringent quality protocols to ensure isotopic purity, chemical purity, and specific activity. Our products undergo rigorous quality testing, including radiochemical purity analysis by HPLC or TLC, specific activity determination, and chemical assay. Certificates of Analysis (COA) detailing all test results, including radionuclidic purity and solvent content, are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended cold temperatures (typically 2-8°C or as specified on the label) to maintain stability and specific activity. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment. Handle and store in accordance with all local, national, and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid or solution
Identification (IR/NMR)	Conforms
Radiochemical Purity (HPLC/TLC)	≥ 95%
Specific Activity	Customized (Ci/mmol or GBq/mmol)
Chemical Purity (Assay)	≥ 98%
Solvent (if supplied in solution)	Specified (e.g., Diglyme, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.