Description

3,3,5,5-D4-Morpholine is a deuterated analog of morpholine, a versatile heterocyclic amine. This isotopically labeled compound is critical for advanced research and development, particularly in analytical chemistry and pharmaceutical studies. It is primarily used by scientists and manufacturers in the pharmaceutical, agrochemical, and material science industries who require deuterated standards for applications such as NMR spectroscopy, mass spectrometry, and metabolic research.

Application

• As an internal standard or reference material in quantitative NMR (Nuclear Magnetic Resonance) spectroscopy and LC-MS (Liquid Chromatography-Mass Spectrometry).
• As a deuterated building block in the synthesis of labeled pharmaceutical compounds for drug metabolism and pharmacokinetics (DMPK) studies.
• For use in mechanistic studies and reaction pathway elucidation in organic and catalytic chemistry.
• In the development and calibration of analytical methods where a non-interfering, isotopically pure standard is required.
• As a precursor in the synthesis of specialty polymers and advanced materials where deuterium incorporation is needed.
• For fundamental research in physical chemistry, including studies on solvent effects and hydrogen-deuterium exchange.

Basic Information

Product Name	3,3,5,5-D4-Morpholine
CAS No.	35530-94-0
Molecular Formula	C4H4D4NO
Molecular Weight	91.14 g/mol
Synonyms	Perdeuterated Morpholine (d8); Morpholine-d8; Tetradeuterated Morpholine; 1-Oxa-4-azacyclohexane-3,3,5,5-d4; Deuterated Morpholine; 3,3,5,5-Tetradeuteromorpholine; Morpholine-3,3,5,5-d4
EINECS	Contact for details

Quality Control

Our 3,3,5,5-D4-Morpholine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR and GC-MS, to confirm isotopic purity, chemical purity, and identity. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.