Description

Saxitoxin CAS NO 35523-89-8 is a potent, naturally occurring neurotoxin belonging to the paralytic shellfish poison (PSP) family. It is a critical reference standard and research chemical for studying sodium channel function and developing detection methods for marine biotoxins. This high-purity compound is essential for analytical laboratories, regulatory agencies, and research institutions focused on food safety, pharmacology, and neurobiology.

Application

• Analytical Reference Standard: Primary calibration standard for the quantitative analysis of Paralytic Shellfish Toxins (PSTs) in seafood and water samples via HPLC, LC-MS/MS, and mouse bioassay methods.
• Pharmacological Research: A selective and reversible blocker of voltage-gated sodium channels (NaV), used to study channel structure, function, and the mechanisms of neural signal transmission.
• Toxicology & Safety Testing: Used in the development and validation of diagnostic assays, biosensors, and antidote research for shellfish poisoning.
• Neuroscience Studies: A vital tool for investigating synaptic transmission, neuronal excitability, and the pathophysiology of conditions related to sodium channel dysfunction.
• Environmental Monitoring: Calibrating detection kits and instruments for monitoring harmful algal blooms (HABs) and ensuring compliance with seafood safety regulations worldwide.
• Biomedical Research: Serves as a molecular probe in studies of ion channel diseases, neuropathic pain, and cardiac electrophysiology.

Basic Information

Product Name	Saxitoxin
CAS No.	35523-89-8
Molecular Formula	C10H17N7O4
Molecular Weight	299.29 g/mol
Synonyms	STX; Saxitoxin dihydrochloride; Paralytic Shellfish Poison; Gonyautoxin; Mussel poison; Clam poison; PSP toxin; (+)-Saxitoxin; Saxitoxin hydrochloride; 2,6-Diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-1H,8H-pyrrolo[3,2-c]purine-8,10(3H)-dione
EINECS	Contact for details

Quality Control

Our Saxitoxin is produced and handled under strict quality protocols to ensure the highest purity and stability for research and analytical applications. Each batch is characterized using advanced analytical techniques, including NMR, HPLC, and MS, to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and chromatographic data is provided with every shipment to support your compliance and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or desiccant after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Potency)	Contact for details
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.