Description

Bongkrekic Acid CAS NO 11076-19-0 is a potent, highly specific mitochondrial toxin produced by the bacterium *Burkholderia gladioli*. This compound is a critical tool in biochemical and pharmacological research for its ability to inhibit the mitochondrial adenine nucleotide translocator (ANT), thereby inducing apoptosis. It is essential for researchers and professionals studying mitochondrial function, cellular metabolism, and mechanisms of cell death. Our supply ensures high-purity material for reliable and reproducible experimental results in academic, pharmaceutical, and biotechnology settings.

Application

• Mitochondrial Research: Used as a specific inhibitor to study adenine nucleotide transport, mitochondrial permeability transition pore (MPTP) formation, and bioenergetics.
• Apoptosis & Cell Death Studies: Employed to induce and investigate intrinsic apoptotic pathways in various cell lines and model organisms.
• Pharmacology & Toxicology: Serves as a reference toxin and a tool compound for screening potential protective agents against mitochondrial dysfunction.
• Biochemical Assay Development: Utilized in developing and validating assays for mitochondrial membrane potential and ATP/ADP flux.
• Food Safety Research: Studied as a model toxin in understanding and preventing contamination by *B. gladioli*, particularly in fermented food products.
• Academic & Industrial R&D: Provides a key reagent for fundamental research in cell biology and for drug discovery programs targeting mitochondrial pathways.

Basic Information

Product Name	Bongkrekic Acid
CAS No.	11076-19-0
Molecular Formula	C28H38O7
Molecular Weight	486.60 g/mol
Synonyms	Bongkrek Acid; Toxoflavin; Bongkrek toxin; Burkholderia toxin; 3-Carboxy-2-hydroxy-4-methoxy-4,6-dimethyl-5-[(1E,3E,5E,7E)-8-[(2R,3S)-3-hydroxy-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-3,7-dimethylocta-1,3,5,7-tetraenyl]benzoic acid
EINECS	Contact for details

Quality Control

Our Bongkrekic Acid is produced and handled under strict quality protocols to ensure the highest standards for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters to guarantee batch-to-batch consistency and reliability for your sensitive research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Biological Activity	Confirmed by mitochondrial assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.