Description

Ciguatoxin CAS NO 11050-21-8 is a potent, naturally occurring marine neurotoxin primarily responsible for ciguatera fish poisoning (CFP). It is a critical reference standard and research chemical for analytical, toxicological, and pharmacological studies. This high-purity compound is essential for laboratories in the food safety, environmental monitoring, and biomedical research sectors to develop detection methods, study toxin mechanisms, and ensure public health protection.

Application

• Analytical Reference Standard: Primary use as a certified standard for the calibration and validation of analytical methods like LC-MS/MS and ELISA for ciguatoxin detection in seafood.
• Food Safety Testing: Development and quality control of commercial test kits and laboratory protocols to screen fish samples for ciguatera poisoning risk.
• Toxicology Research: In-vitro and in-vivo studies to investigate the acute and chronic effects, toxicokinetics, and dose-response relationships of ciguatoxins.
• Pharmacology Studies: Research into the mechanism of action on voltage-gated sodium channels and the development of potential therapeutic antidotes for CFP.
• Environmental Monitoring: Used in programs to study the biogeography of toxin-producing dinoflagellates (Gambierdiscus spp.) and the impact of climate change on toxin distribution.
• Regulatory Compliance: Supporting regulatory bodies and public health agencies in establishing and enforcing safe limits for toxins in seafood.

Basic Information

Product Name	Ciguatoxin
CAS No.	11050-21-8
Molecular Formula	C60H86O19
Molecular Weight	1111.3 g/mol
Synonyms	CTX; Ciguatoxin-1; Ciguatoxin CTX1B; P-CTX-1; Pacific Ciguatoxin-1; (2S,4R,6R,14R,16R,18R,20R,21R,23R,25R,27R,29R,31R,33R,35R,37R,39R,41R,43R,45R,47R,49R,51R,53R,55R,57R,59R)-2,4,6,14,16,18,20,21,23,25,27,29,31,33,35,37,39,41,43,45,47,49,51,53,55,57,59-Heptacosahydroxy-3,5,7,15,17,19,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60-hexacosamethoxy-8,12,61,61-tetramethyl-62-oxapentacyclo[55.3.1.13,7.19,13.139,43]henhexaconta-1(61),3,5,9(69),10,12,39(68),40,42,44,46,48,50,52,54,56-hexadecaen-63-one
EINECS	Contact for details

Quality Control

Our Ciguatoxin is produced and handled under strict quality-controlled environments to ensure the highest purity and stability for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to rigorous internal standards to guarantee batch-to-batch consistency and reliability for your critical research and analytical work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Store under an inert atmosphere. The product is hygroscopic and should be handled in a dry environment to prevent degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.