Description

2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) is a highly potent and well-characterized member of the polychlorinated dibenzo-p-dioxin (PCDD) family, recognized as the most toxic congener. This compound is of paramount importance for scientific research, environmental monitoring, and regulatory compliance testing. It is primarily required by analytical laboratories, environmental agencies, and research institutions for use as a critical analytical reference standard in the detection and quantification of dioxin contamination.

Application

• Analytical Reference Standard: Primary use as a certified standard for calibrating GC-MS and HRGC/HRMS systems in environmental and food safety testing.
• Environmental Analysis: Critical for the detection and quantification of dioxin levels in soil, water, sediment, and air samples to assess pollution and remediation efforts.
• Food and Feed Safety Testing: Used in laboratories to monitor and ensure compliance with strict international limits for dioxins in the food chain.
• Toxicological Research: Serves as a key compound in studies investigating the mechanisms of dioxin toxicity, endocrine disruption, and long-term health effects.
• Method Development and Validation: Essential for developing, optimizing, and validating new analytical methods for trace-level dioxin analysis.
• Quality Control/Quality Assurance (QC/QA): Employed in laboratory proficiency testing and internal quality control programs to ensure analytical accuracy.
• Regulatory Compliance: Supports testing mandated by regulations such as EPA Method 1613, EU regulations, and other global directives.
• Waste and Emission Monitoring: Used to analyze dioxin emissions from industrial processes like waste incineration and chemical manufacturing.

Basic Information

Product Name	2,3,7,8-Tetrachlorodibenzo-p-Dioxin
CAS No.	1746-01-6
Molecular Formula	C₁₂H₄Cl₄O₂
Molecular Weight	321.98 g/mol
Synonyms	TCDD; 2,3,7,8-TCDD; Dioxin; Tetradioxin; 2,3,7,8-Tetrachlorodibenzodioxin; 2,3,7,8-Tetrachlorodibenzo[b,e][1,4]dioxin; Dibenzo[b,e][1,4]dioxin, 2,3,7,8-tetrachloro-
EINECS	217-122-7

Quality Control

Our high-purity 2,3,7,8-Tetrachlorodibenzo-p-Dioxin is manufactured and handled under strict quality protocols to ensure identity, purity, and stability for critical analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chromatographic data, and verification against certified reference materials. We adhere to ISO 17034 guidelines for reference material producers, and our quality system supports traceability and data integrity for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at or below -20°C under an inert atmosphere to minimize the risk of degradation. The container should be kept in a dedicated, well-ventilated area designated for highly toxic substances. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or solution
Identification (HPLC/GC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0% (Area %)
Purity (GC-MS)	≥ 99.0% (for certified reference material grade)
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Solvent Content (Residual Solvents)	Meets ICH guidelines
Concentration (for solutions)	10 µg/mL ± 5% in nonane, toluene, or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.