Description

Thiazolo[5,4-f]isoquinolin-2(3H)-one (9CI) is a specialized heterocyclic organic compound belonging to the fused thiazolo-isoquinoline class. This high-purity chemical building block is valued for its unique molecular scaffold, which is critical for advanced research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D teams and academic research institutions engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to explore new pharmacophores.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct more elaborate heterocyclic systems.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Academic & Institutional R&D: Fundamental research in universities and government labs for exploring new chemical entities and reaction methodologies.
• Contract Research Organizations (CROs): Sourced by CROs for client-sponsored drug discovery programs requiring specialized intermediates.

Basic Information

Item	Detail
Product Name	Thiazolo[5,4-f]isoquinolin-2(3H)-one (9CI)
CAS No.	35352-74-0
Molecular Formula	C10H6N2OS
Molecular Weight	202.23 g/mol
Synonyms	2H-Thiazolo[5,4-f]isoquinolin-2-one; Thiazolo[5,4-f]isoquinolin-2(3H)-one; 35352-74-0; Thiazolo[5,4-f]isoquinolin-2-ol; 2H-Thiazolo[5,4-f]isoquinolin-2-one, 9CI; Thiazolo[5,4-f]isoquinolin-2(1H)-one (alternative tautomer notation)
EINECS	Contact for details

Quality Control

Our Thiazolo[5,4-f]isoquinolin-2(3H)-one is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.