Description

5-Isoquinolinethiol,8-Amino-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines an amino group and a thiol functionality on an isoquinoline scaffold, enabling its use in the development of novel pharmacophores and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecular entities with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Ligand Synthesis: Used in the preparation of chelating ligands for catalysis or metal-organic frameworks (MOFs) due to its sulfur and nitrogen donor atoms.
• Agrochemical Research: Employed in the discovery and development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of advanced polymers and conductive materials.
• Chemical Biology Probe: Utilized in the design of probes for studying enzyme mechanisms or protein interactions via its reactive thiol group.
• Dye and Pigment Intermediate: Functions as a building block for synthesizing novel heterocyclic dyes with specific optical properties.

Basic Information

Item	Detail
Product Name	5-Isoquinolinethiol,8-Amino-(9Ci)
CAS No.	35317-96-5
Molecular Formula	C9H8N2S
Molecular Weight	176.24 g/mol
Synonyms	8-Aminoisoquinoline-5-thiol; 8-Amino-5-mercaptoisoquinoline; 5-Mercapto-8-aminoisoquinoline; 8-Amino-5-isoquinolinethiol; 35317-96-5; 8-Aminoisoquinoline-5-thiol (9CI); 5-Thiol-8-aminoisoquinoline
EINECS	Contact for details

Quality Control

Our 5-Isoquinolinethiol,8-Amino-(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR/NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.