Description

8-Isoquinolinethiol,5-Amino-(9Ci) CAS NO 35317-94-3 is a specialized heterocyclic building block featuring both amino and thiol functional groups on an isoquinoline scaffold. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and functional ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for targeting neurological disorders and cancers.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic core.
• Ligand Synthesis: Serves as a building block for creating chelating agents and catalysts in metal-organic chemistry and homogeneous catalysis.
• Material Science: Employed in the development of organic semiconductors, conductive polymers, and advanced functional materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or affinity probes for studying biological systems and protein interactions.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to form complex carbon-sulfur and carbon-nitrogen bonds.

Basic Information

Product Name	8-Isoquinolinethiol,5-Amino-(9Ci)
CAS No.	35317-94-3
Molecular Formula	C9H8N2S
Molecular Weight	176.24 g/mol
Synonyms	5-Aminoisoquinoline-8-thiol; 5-Amino-8-mercaptoisoquinoline; 8-Mercapto-5-aminoisoquinoline; 5-Amino-8-thiohydroxyisoquinoline; 5-Amino-8-sulfanylisoquinoline; 8-Thiol-5-aminoisoquinoline; AIQ-8-thiol; 35317-94-3
EINECS	Contact for details

Quality Control

Every batch of 8-Isoquinolinethiol,5-Amino-(9Ci) is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Purity (HPLC)	≥ 98% (High Purity Grade)
Melting Point	Contact for details
Water Content (KF)	< 1.0 %
Residue on Ignition	< 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.