Description

2-(4-Bromophenyl)-4-(Chloromethyl)-1,3-Thiazole is a high-value brominated and chloromethylated heterocyclic building block, primarily utilized in advanced organic synthesis. Its molecular structure makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in oncology and antiviral research pipelines.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated thiazole core.
• Material Science Research: Serves as a precursor for functionalized polymers and liquid crystals due to its aromatic and reactive chloromethyl group.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-(4-Bromophenyl)-4-(Chloromethyl)-1,3-Thiazole
CAS No.	35199-19-0
Molecular Formula	C10H7BrClNS
Molecular Weight	288.59 g/mol
Synonyms	4-(Chloromethyl)-2-(4-bromophenyl)thiazole; 2-(4-Bromophenyl)-4-(chloromethyl)thiazole; 4-(Chloromethyl)-2-(p-bromophenyl)thiazole; 2-(p-Bromophenyl)-4-(chloromethyl)thiazole; 1,3-Thiazole, 2-(4-bromophenyl)-4-(chloromethyl)-; 35199-19-0; 4-(Chloromethyl)-2-(4'-bromophenyl)thiazole
EINECS	Contact for details

Quality Control

Our production of 2-(4-Bromophenyl)-4-(Chloromethyl)-1,3-Thiazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.