Description

7-Hydroxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound is a key chiral intermediate valued for its structural complexity and functional groups, enabling the construction of sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), fine chemicals, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials requiring precise stereochemistry.
• Research & Development: Serves as a standard or starting material in medicinal chemistry and process chemistry R&D for exploring new synthetic pathways.
• Peptidomimetics & Bioactive Molecules: Its structure makes it suitable for constructing peptidomimetic scaffolds and other molecules designed to interact with biological targets.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.

Basic Information

Product Name	7-Hydroxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	35186-98-2
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	7-Hydroxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid; 7-Hydroxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 3-Carboxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline; 7-Hydroxy-Tic-OH; (R/S)-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Hydroxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the stringent requirements of research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.