Description

(2R,5S)-2-(1-Mercapto-1-Methylethyl)-5-Methylcyclohexanone is a high-purity chiral intermediate with a distinct mercaptoketone structure, offering significant value in asymmetric synthesis. Its precise stereochemistry makes it a critical building block for creating complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active ingredients and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in areas requiring stereochemical control.
• Fine Chemical Synthesis: Used in the production of complex, high-value specialty chemicals where its unique mercapto and ketone functionalities are leveraged.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel catalytic systems for enantioselective reactions.
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing specific, high-value aroma chemicals with defined olfactory characteristics.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and stereochemistry at research institutions and corporate labs.

Basic Information

Product Name	(2R,5S)-2-(1-Mercapto-1-Methylethyl)-5-Methylcyclohexanone
CAS No.	35117-86-3
Molecular Formula	C11H20OS
Molecular Weight	200.34 g/mol
Synonyms	(-)-Menthone Mercaptan; (1R,2S,5R)-2-(2-Mercaptopropan-2-yl)-5-methylcyclohexan-1-one; 2-(1-Mercapto-1-methylethyl)-5-methylcyclohexanone; L-Menthone mercaptan; p-Menthane-8-thiol-3-one; 8-Mercapto-p-menthan-3-one
EINECS	Contact for details

Quality Control

Our (2R,5S)-2-(1-Mercapto-1-Methylethyl)-5-Methylcyclohexanone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to verify identity, enantiomeric excess, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources. Due to the light-sensitive nature of the compound, containers should be amber glass or otherwise light-protected.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.