Description

10,11-Dihydro-10,11-Dihydroxy-5H-Dibenzazepine-5-Carboxamide is a high-purity pharmaceutical intermediate and organic building block of significant commercial interest. This compound is a key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly in the central nervous system (CNS) therapeutic area. It is primarily sought after by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical suppliers engaged in advanced synthesis. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency for critical R&D and production processes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, especially tricyclic antidepressants and related neuroactive compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for the research and development of new chemical entities targeting neurological disorders.
• Biochemical Research: Used in academic and industrial laboratories for pharmacological studies and as a reference standard.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex organic molecules with the dibenzazepine core structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	10,11-Dihydro-10,11-Dihydroxy-5H-Dibenzazepine-5-Carboxamide
CAS No.	35079-97-1
Molecular Formula	C15H14N2O3
Molecular Weight	270.28 g/mol
Synonyms	10,11-Dihydro-10,11-dihydroxycarbamazepine; 10,11-Dihydro-10,11-dihydroxy-5H-dibenz[b,f]azepine-5-carboxamide; Carbamazepine-10,11-dihydrodiol; trans-10,11-Dihydro-10,11-dihydroxycarbamazepine; CBZ-diol; NSC 169864; 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10,11-dihydroxy-
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-10,11-Dihydroxy-5H-Dibenzazepine-5-Carboxamide is produced and tested under a strict quality management system. We provide material suitable for pharmaceutical research and development, with specifications tailored to meet client requirements. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to ensure full traceability and compliance with your quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.