Description

Nicomorphine Hydrochloride is a semi-synthetic opioid analgesic derived from morphine, distinguished by its enhanced potency and specific pharmaceutical applications. This compound is critical for advanced pain management research and development, offering a valuable tool for studying opioid receptor pharmacology. It is primarily utilized by pharmaceutical R&D laboratories, analytical reference standard providers, and specialized chemical manufacturers serving the life sciences sector.

Application

• Pharmaceutical Reference Standard: Used as a certified standard in analytical testing (HPLC, GC-MS) for quality control and method validation in pharmaceutical labs.
• Biomedical Research: Serves as a key reagent in preclinical studies investigating opioid analgesic pathways, receptor binding, and metabolic profiles.
• Controlled Substance Analysis: Employed by forensic and toxicology laboratories for the identification and quantification of opioids in compliance and legal cases.
• Advanced Drug Formulation R&D: Used in the development and testing of novel, high-potency analgesic formulations under controlled research settings.
• Chemical Synthesis Intermediate: Acts as a specialized intermediate for the synthesis of other morphinan derivatives in advanced organic chemistry.

Basic Information

Product Name	Nicomorphine Hydrochloride
CAS No.	35055-78-8
Molecular Formula	C₂₉H₃₀N₂O₄ · HCl
Molecular Weight	515.02 g/mol
Synonyms	6-Nicotinoylmorphine Hydrochloride; Vilan® Hydrochloride; Nicomorphine HCl; Morphine-6-nicotinate Hydrochloride; 3,6-Dinicotinoylmorphine Hydrochloride; 4,5α-Epoxy-17-methyl-7,8-didehydromorphinan-3,6α-diol Di-3-pyridinecarboxylate Hydrochloride
EINECS	Contact for details

Quality Control

Our Nicomorphine Hydrochloride is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support our clients' compliance needs in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local, national, and international regulations for controlled substances.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.