Description

5-Oxazolidinone,4-Methyl-2-(2-Oxopropylidene)-,[S-(E)]-(9Ci) is a specialized chiral oxazolidinone derivative, a class of compounds renowned for their utility as versatile synthetic intermediates and auxiliaries in asymmetric synthesis. This high-purity compound is critical for researchers and manufacturers requiring precise stereochemical control in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. Its unique structure makes it a valuable building block for medicinal chemistry, process R&D, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of complex drug molecules, particularly in constructing β-lactam and other heterocyclic frameworks.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Auxiliary: Functions as a chiral controller in Evans-type aldol and alkylation reactions to induce high enantioselectivity.
• Organic Synthesis & Process Chemistry: Employed in academic and industrial R&D for constructing novel organic molecules with defined stereocenters.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring chiral purity.

Basic Information

Product Name	5-Oxazolidinone,4-Methyl-2-(2-Oxopropylidene)-,[S-(E)]-(9Ci)
CAS No.	35006-45-2
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	(S,E)-4-Methyl-2-(2-oxopropylidene)-1,3-oxazolidin-5-one; (S,E)-4-Methyl-2-(2-oxopropylidene)oxazolidin-5-one; (4S)-4-Methyl-2-[(1E)-2-oxopropylidene]-1,3-oxazolidin-5-one; (S)-4-Methyl-2-(2-oxopropylidene)-5-oxazolidinone; Evans Oxazolidinone Derivative; Chiral Oxazolidinone Auxiliary
EINECS	Contact for details

Quality Control

Our 5-Oxazolidinone,4-Methyl-2-(2-Oxopropylidene)-,[S-(E)]-(9Ci) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including chiral HPLC, NMR, and mass spectrometry to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.