Description

(tert-Butoxycarbonylmethyl)Triphenylphosphonium Chloride is a high-purity, crystalline phosphonium salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a stabilized ylide precursor for the Wittig reaction, enabling the efficient synthesis of α,β-unsaturated esters and other valuable olefins. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality building blocks for complex molecule construction.

Application

• As a key Wittig reagent for the synthesis of α,β-unsaturated esters (dehydroamino acid derivatives) and other olefins.
• Intermediate in the multi-step synthesis of complex pharmaceutical actives, including peptide mimetics and enzyme inhibitors.
• Building block for agrochemical research, particularly in creating compounds with specific stereochemistry.
• Precursor in material science for the development of specialty polymers and functionalized organic molecules.
• Used in academic and industrial R&D for methodology development and exploring new chemical spaces.
• Facilitates the introduction of the tert-butoxycarbonyl (Boc)-protected glycine moiety into target molecules via olefination.

Basic Information

Product Name	(tert-Butoxycarbonylmethyl)Triphenylphosphonium Chloride
CAS No.	35000-37-4
Molecular Formula	C24H26ClO2P
Molecular Weight	412.89 g/mol
Synonyms	(Carboxymethyl)triphenylphosphonium Chloride tert-Butyl Ester; (Boc-methyl)triphenylphosphonium Chloride; 2-(tert-Butoxy)-2-oxoethylidenetriphenylphosphorane Chloride; tert-Butoxycarbonylmethyltriphenylphosphonium Chloride; Boc-CH2-PPh3 Cl; N-(tert-Butoxycarbonyl)methyltriphenylphosphonium Chloride; Triphenylphosphonium (tert-butoxycarbonyl)methyl Chloride
EINECS	Contact for details

Quality Control

Our (tert-Butoxycarbonylmethyl)Triphenylphosphonium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	~195-205°C (dec.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.