Description

8-Chloroisoquinoline is a versatile halogenated heterocyclic compound serving as a critical building block in advanced organic synthesis. Its value lies in its unique fused-ring structure, which provides a rigid scaffold for constructing complex molecules with targeted biological or material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Academic & R&D: A fundamental reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	8-Chloroisoquinoline
CAS No.	34784-07-1
Molecular Formula	C9H6ClN
Molecular Weight	163.60 g/mol
Synonyms	Isoquinoline, 8-chloro-; 8-Chloro-isoquinoline; 8-Chloroisoquinoline; NSC 406919; 8-Chloro-1-azanaphthalene; 8-Chloro-2-azanaphthalene; 8-Chlorobenzo[f]quinoline (incorrect but common misnomer); 8-Cl-IQ
EINECS	Contact for details

Quality Control

Our 8-Chloroisoquinoline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.