Description

4-Chloromethyl-Thiophene-2-Carboxylic Acid Methyl Ester is a versatile and high-purity chemical building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its reactive chloromethyl and ester functionalities enable critical structural modifications. It is primarily needed by research chemists and process development teams in pharmaceutical R&D, agrochemical manufacturing, and material science for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing thiophene scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene ring for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and the creation of novel chemical libraries.
• Ligand and Catalyst Preparation: Useful for synthesizing complex ligands for metal catalysis or functionalized catalysts.
• Fine Chemical Production: Acts as an intermediate in the multi-step synthesis of other high-value, specialized fine chemicals.

Basic Information

Product Name	4-Chloromethyl-Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	34767-85-6
Molecular Formula	C8H7ClO2S
Molecular Weight	202.65 g/mol
Synonyms	Methyl 4-(chloromethyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-(chloromethyl)-, methyl ester; Methyl 4-chloromethylthiophene-2-carboxylate; 4-Chloromethyl-2-thiophenecarboxylic acid methyl ester; 4-(Chloromethyl)thiophene-2-carboxylic acid methyl ester; 2-Carbomethoxy-4-chloromethylthiophene
EINECS	Contact for details

Quality Control

Every batch of 4-Chloromethyl-Thiophene-2-Carboxylic Acid Methyl Ester undergoes rigorous quality testing to ensure compliance with stringent industry standards. Our quality assurance protocols are designed to guarantee batch-to-batch consistency, high purity, and reliable performance in your synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality management and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to minimize exposure to moisture. Store away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.