Description

2-Acetyl-4-Chlorothiophene is a versatile and high-purity organic building block, specifically a substituted thiophene derivative. This compound is valued for its unique molecular structure, which makes it a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing thiophene or chlorinated heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive acetyl and chloro functional groups.
• Material Science Research: Serves as a precursor for functionalized polymers, organic semiconductors, and liquid crystals due to the electron-rich thiophene ring.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a starting material for creating more complex fused-ring systems and ligands for catalysis.
• Dye and Pigment Intermediate: Utilized in the development of specialized dyes and organic pigments where the thiophene moiety imparts specific color and stability properties.

Basic Information

Product Name	2-Acetyl-4-Chlorothiophene
CAS No.	34730-20-6
Molecular Formula	C6H5ClOS
Molecular Weight	160.62 g/mol
Synonyms	1-(4-Chloro-2-thienyl)ethanone; 4-Chloro-2-acetylthiophene; 4-Chloro-2-thienyl methyl ketone; 2-Acetyl-4-chlorothiophene; 4-Chloro-2-thienyl ketone; 4-Chloro-2-thiophenecarbaldehyde, acetyl-; 1-(4-Chlorothiophen-2-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Every batch of 2-Acetyl-4-Chlorothiophene is manufactured and tested under a strict quality management system. We ensure high chemical purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.