Description

2-(Bromomethyl)Tetrahydro-2 H-Pyran is a versatile brominated heterocyclic building block used in advanced organic synthesis. This compound is valued for its reactive bromomethyl group, which facilitates efficient alkylation and functionalization reactions under controlled conditions. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing tetrahydropyran or morpholine-like scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the tetrahydropyran moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and polymerization processes.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering physical properties for advanced material science applications.
• Cross-coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Protecting Group Chemistry: The tetrahydropyranyl (THP) derivative can be utilized in multi-step syntheses to protect alcohol functionalities.

Basic Information

Product Name	2-(Bromomethyl)Tetrahydro-2 H-Pyran
CAS No.	34723-82-5
Molecular Formula	C6H11BrO
Molecular Weight	179.06 g/mol
Synonyms	2-(Bromomethyl)oxane; 2-(Bromomethyl)tetrahydropyran; Tetrahydro-2H-pyran-2-ylmethyl bromide; 2-Bromomethyltetrahydropyran; Oxan-2-ylmethyl bromide; 2-Pyranylmethyl bromide, tetrahydro-; THP-2-ylmethyl bromide
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)Tetrahydro-2 H-Pyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.