Description

3-Amino-5-Nitro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity, heterocyclic organic building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing novel thiophene-based scaffolds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its nitro and amino functional groups for structural modification.
• Dye and Pigment Synthesis: Serves as a building block for creating specialized heterocyclic dyes and organic pigments due to its conjugated thiophene core.
• Material Science: Investigated as a monomer or precursor for conductive polymers and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development, such as novel cross-coupling or cyclization reactions.

Basic Information

Product Name	3-Amino-5-Nitro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	34674-75-4
Molecular Formula	C10H8N2O4S
Molecular Weight	252.25 g/mol
Synonyms	Methyl 3-amino-5-nitrobenzo[b]thiophene-2-carboxylate; 3-Amino-5-nitro-2-benzothiophenecarboxylic acid methyl ester; 2-Benzothiophenecarboxylic acid, 3-amino-5-nitro-, methyl ester; Methyl 3-amino-5-nitro-1-benzothiophene-2-carboxylate; 5-Nitro-3-aminothianaphthene-2-carboxylic acid methyl ester; 3-Amino-5-nitro-thianaphthene-2-carboxylic acid methyl ester; Benzo[b]thiophene-2-carboxylic acid, 3-amino-5-nitro-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Nitro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.