Description

(-)-Methylphenylphosphinic Acid Methyl Ester is a chiral organophosphorus compound of significant interest in asymmetric synthesis and catalysis. Its value lies in its utility as a versatile building block and ligand precursor for creating stereoselective catalysts. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity chiral intermediates for the development of novel active ingredients and materials.

Application

• Chiral Ligand Synthesis: A key precursor for the preparation of enantiomerically pure phosphine and phosphinite ligands used in asymmetric hydrogenation and other catalytic transformations.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of chiral active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• Agrochemical Development: Used in the research and production of enantiomerically defined herbicides, fungicides, and plant growth regulators.
• Catalyst Research: Employed in academic and industrial R&D for developing new metal-complex catalysts for stereoselective organic reactions.
• Material Science: Potential applications in the synthesis of chiral polymers or advanced materials with specific optical properties.

Basic Information

Product Name	(-)-Methylphenylphosphinic Acid Methyl Ester
CAS No.	34647-06-8
Molecular Formula	C9H13O2P
Molecular Weight	184.17 g/mol
Synonyms	(-)-Methyl Phenylphosphinate; (R)-(-)-Methyl Phenylphosphinate; Methyl (R)-(-)-Phenylphosphinate; Methyl (R)-Phenylphosphinate; (R)-Methyl Phenylphosphinate; Phenylphosphinic Acid Methyl Ester, (R)-(-)-; Methyl Phenylphosphonite (common misnomer); L-Methyl Phenylphosphinate
EINECS	Contact for details

Quality Control

Our (-)-Methylphenylphosphinic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity and purity. Certificates of Analysis (COA) detailing specific parameters such as assay, enantiomeric excess (ee), and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.