Description

(+)-Methylphenylphosphinic Acid Ethyl Ester CAS NO 34638-79-4 is a high-purity, chiral organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its enantiomerically pure structure makes it an essential building block for the development of pharmaceuticals, agrochemicals, and specialty materials. This product is particularly valuable for research institutions and industrial manufacturers engaged in asymmetric synthesis, ligand development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Catalyst & Ligand Precursor: Used in the preparation of chiral phosphine ligands for transition metal catalysis, enabling highly enantioselective reactions.
• Agrochemical Synthesis: Serves as a building block for creating novel, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science Research: Employed in the development of chiral polymers, liquid crystals, and advanced functional materials.
• Asymmetric Organic Synthesis: A versatile reagent for academic and industrial research in constructing complex, stereodefined molecular architectures.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in chiral analysis.

Basic Information

Product Name	(+)-Methylphenylphosphinic Acid Ethyl Ester
CAS No.	34638-79-4
Molecular Formula	C9H13O2P
Molecular Weight	184.17 g/mol
Synonyms	(R)-(+)-Methylphenylphosphinic Acid Ethyl Ester; Ethyl (R)-(+)-Methylphenylphosphinate; (R)-Ethyl Methylphenylphosphinate; (+)-Ethyl Methylphenylphosphinate; P-Methyl-P-phenylphosphinic Acid Ethyl Ester; Ethyl Methyl(phenyl)phosphinate; (R)-Ethyl Methyl(phenyl)phosphinate; Ethyl α-Methylbenzenephosphinate
EINECS	Contact for details

Quality Control

Our (+)-Methylphenylphosphinic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]D20	+30.0° to +35.0° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.