Description

4-Ethyl-1,3-thiazol-2-amine hydrochloride hemihydrate is a high-purity organic salt of a substituted thiazole amine, a versatile heterocyclic building block of significant commercial interest. Its primary value lies in its role as a critical synthetic intermediate for the development of advanced pharmaceuticals, agrochemicals, and specialty chemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the 2-aminothiazole pharmacophore into novel molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a core building block for developing novel fungicides, herbicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and complex organic ligands for catalysis and material science applications.
• Research & Development: A valuable reagent in medicinal chemistry and organic synthesis for constructing heterocyclic libraries and exploring structure-activity relationships (SAR).
• Chemical Reference Standard: Supplied as a high-purity compound for analytical testing, method development, and quality control in regulatory and laboratory settings.

Basic Information

Product Name	4-Ethyl-1,3-thiazol-2-amine hydrochloride hemihydrate
CAS No.	34631-53-3
Molecular Formula	C5H8N2S • HCl • 0.7H2O
Molecular Weight	~179.66 g/mol (anhydrous salt basis)
Synonyms	2-Amino-4-ethylthiazole hydrochloride hemihydrate; 4-Ethyl-2-aminothiazole hydrochloride hemihydrate; 4-Ethylthiazol-2-amine hydrochloride hemihydrate; 4-Ethyl-1,3-thiazol-2-amine monohydrochloride hemihydrate; 2-Amino-4-ethyl-1,3-thiazole HCl 0.7H2O; 4-Ethyl-2-thiazolamine hydrochloride hydrate; 4-Ethyl-1,3-thiazol-2-amine (Saltdata: HCl 0.7H2O)
EINECS	Contact for details

Quality Control

Our 4-Ethyl-1,3-thiazol-2-amine hydrochloride hemihydrate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	4.0% - 7.0% (hemihydrate)
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.