Description

Nortilidine Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry. Its primary value lies in its role as a key synthetic precursor for the development of novel therapeutic agents, particularly within the central nervous system (CNS) domain. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in the early-stage development and scale-up of potential new drugs.
• Academic Research: Utilized in university and institutional labs for chemical synthesis projects and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Nortilidine Hydrochloride
CAS No.	34596-11-7
Molecular Formula	C15H21NO2·HCl
Molecular Weight	283.79 g/mol (Free base: 247.33 g/mol)
Synonyms	1-Methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester hydrochloride; Ethyl 1-methyl-4-phenyl-4-piperidinecarboxylate hydrochloride; Pethidine intermediate; Meperidine impurity standard; Pethidine related compound A; Norpethidine hydrochloride; Ethyl norpethidinate hydrochloride
EINECS	Contact for details

Quality Control

Our Nortilidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.