Description

(S)-(+)-3-Quinuclidinol CAS NO 34583-34-1 is a high-purity, chiral bicyclic amino alcohol of significant importance in asymmetric synthesis and pharmaceutical development. Its rigid, three-dimensional quinuclidine scaffold serves as a versatile and privileged chiral building block for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Chiral Ligand & Catalyst Synthesis: A key precursor for synthesizing chiral ligands and organocatalysts used in asymmetric hydrogenation, alkylation, and other enantioselective transformations.
• Pharmaceutical Intermediate: A critical building block in the synthesis of muscarinic receptor antagonists, antispasmodic agents, and other therapeutically active compounds.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides, where stereochemistry impacts biological activity.
• Fine Chemical Synthesis: Employed in the preparation of complex, high-value specialty chemicals requiring a defined stereocenter.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-(+)-3-Quinuclidinol
CAS No.	34583-34-1
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(S)-(+)-3-Quinuclidinol; (S)-3-Quinuclidinol; (3S)-Quinuclidin-3-ol; (+)-(S)-3-Quinuclidinol; (S)-1-Azabicyclo[2.2.2]octan-3-ol; (S)-3-Hydroxyquinuclidine; (S)-Quinuclidin-3-ol; L-Quinuclidinol
EINECS	Contact for details

Quality Control

Our (S)-(+)-3-Quinuclidinol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing specific results for each parameter is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.