Description

1H-Isoindole-1,3(2H)-Dione, 2-(6-Amino-1,2,3,4-Tetrahydro-1,3-Dimethyl-2,4-Dioxo-5-Pyrimidinyl)- is a high-purity heterocyclic organic compound, also known as a substituted isoindole-1,3-dione derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its molecular structure, featuring both isoindoledione and aminopyrimidinedione moieties, makes it valuable for constructing complex molecules with specific biological activities. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or as enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex polycyclic frameworks and functionalized heterocycles.
• Material Science Research: Potential monomer or precursor for specialty polymers, dyes, or photoactive materials due to its conjugated system.
• Biochemical Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione, 2-(6-Amino-1,2,3,4-Tetrahydro-1,3-Dimethyl-2,4-Dioxo-5-Pyrimidinyl)-
CAS No.	34576-18-6
Molecular Formula	C14H12N4O4
Molecular Weight	300.27 g/mol
Synonyms	2-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)isoindoline-1,3-dione; 5-(1,3-Dioxoisoindolin-2-yl)-6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 6-Amino-1,3-dimethyl-5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)pyrimidine-2,4(1H,3H)-dione; 2-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1H-isoindole-1,3(2H)-dione; Aminophylline Isoindole Derivative; Substituted Theophylline Isoindoledione
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1,3(2H)-Dione derivative is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR, NMR, and MS, to ensure it meets exacting standards for research and production. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Specifications can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.