Description

3-(4-Fluorophenyl)-5,6,7,8-Tetrahydro-2-Methyl[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization, particularly for compounds targeting central nervous system (CNS) or oncological pathways.
• Chemical Biology Probe: Serves as a scaffold for developing tool compounds to study biological mechanisms and enzyme functions in vitro.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material (CTM) production.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental organic chemistry research and custom synthesis projects.

Basic Information

Product Name	3-(4-Fluorophenyl)-5,6,7,8-Tetrahydro-2-Methyl[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	34387-08-1
Molecular Formula	C19H17FN2OS
Molecular Weight	340.42 g/mol
Synonyms	2-Methyl-3-(4-fluorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one; 3-(p-Fluorophenyl)-2-methyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one; 34387-08-1; Fused Thienopyrimidinone Derivative; Benzothienopyrimidinone Intermediate
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-5,6,7,8-Tetrahydro-2-Methyl[1]Benzothieno[2,3-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.