Description

4-(tert-Butyl)-α-Methylbenzyl Alcohol is a chiral aromatic alcohol derivative with a sterically hindered structure. This compound is a versatile chiral intermediate and building block valued for its ability to impart specific stereochemistry and functional properties in advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as asymmetric synthesis and chiral ligand preparation.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing stereocenters.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where specific enantiomeric activity is required.
• Chiral Ligand/Resolve: Serves as a precursor for the development of chiral ligands, catalysts, and resolving agents in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials.
• Research & Development: A valuable standard and starting material in organic chemistry research for method development and novel compound libraries.

Basic Information

Product Name	4-(tert-Butyl)-α-Methylbenzyl Alcohol
CAS No.	34386-42-0
Molecular Formula	C12H18O
Molecular Weight	178.27 g/mol
Synonyms	1-(4-tert-Butylphenyl)ethanol; (RS)-1-(4-tert-Butylphenyl)ethanol; α-Methyl-4-tert-butylbenzenemethanol; p-tert-Butyl-α-methylbenzyl alcohol; 1-(4-(1,1-Dimethylethyl)phenyl)ethanol; 4-tert-Butylphenethyl alcohol (related); 4-(1,1-Dimethylethyl)-α-methylbenzenemethanol
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyl)-α-Methylbenzyl Alcohol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting purity, enantiomeric excess (if applicable), and impurity profiles are available upon request. We support compliance with cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources. For long-term storage under inert atmosphere, please contact for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.