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n-(3-Hydroxypropyl)Maleimide CAS NO 34321-80-7


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CAS No.:34321-80-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(3-Hydroxypropyl)Maleimide is a versatile bifunctional chemical intermediate featuring both a reactive maleimide group and a terminal hydroxyl group. This unique structure makes it a critical building block for synthesizing advanced polymers, functional materials, and bioconjugates. It is essential for researchers and manufacturers in the pharmaceutical, polymer science, and specialty chemical industries seeking to create cross-linked networks, drug delivery systems, or surface-modified materials.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of antibody-drug conjugates (ADCs) and other bioconjugates via thiol-maleimide "click" chemistry.
  • Polymer Cross-linking Agent: Serves as a key monomer or cross-linker in the production of thermosetting resins, hydrogels, and functional polymers.
  • Surface Modification: Enables the covalent attachment of biomolecules or functional groups to surfaces for biosensors, diagnostic assays, and medical devices.
  • Adhesive & Coating Formulations: Imparts enhanced adhesion, durability, and chemical resistance to advanced industrial coatings and adhesives.
  • Material Science Research: A fundamental reagent for developing novel smart materials, self-healing polymers, and controlled-release matrices.

Basic Information

Product Name n-(3-Hydroxypropyl)Maleimide
CAS No. 34321-80-7
Molecular Formula C7H9NO3
Molecular Weight 155.15 g/mol
Synonyms 3-(Maleimid-1-yl)propan-1-ol; 1-(3-Hydroxypropyl)-1H-pyrrole-2,5-dione; N-(3-Hydroxypropyl)maleimide; HPM; Maleimide, N-(3-hydroxypropyl)-; 3-Maleimidopropanol; N-Hydroxypropylmaleimide
EINECS Contact for details

Quality Control

Our n-(3-Hydroxypropyl)Maleimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets high-purity standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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