Description

(1S,2R)-(+)-trans-2-Phenyl-1-Cyclohexanol is a high-purity, chiral cyclohexanol derivative valued for its defined stereochemistry and utility as a versatile synthetic building block. This compound is essential for applications requiring precise molecular geometry, such as the synthesis of complex pharmaceuticals and advanced materials. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for use as a chiral intermediate or resolving agent.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands used in metal-catalyzed asymmetric synthesis to induce enantioselectivity.
• Chiral Resolution Agent: Employed in the separation of racemic mixtures to isolate desired enantiomers in fine chemical production.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or structural properties.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(1S,2R)-(+)-trans-2-Phenyl-1-Cyclohexanol
CAS No.	34281-92-0
Molecular Formula	C₁₂H₁₆O
Molecular Weight	176.26 g/mol
Synonyms	(1S,2R)-2-Phenylcyclohexanol; (+)-trans-2-Phenylcyclohexanol; (1S,2R)-(+)-2-Phenyl-1-cyclohexanol; trans-(1S,2R)-2-Phenylcyclohexan-1-ol; (1S,2R)-2-Phenylcyclohexan-1-ol; Phenylcyclohexanol; 2-Phenylcyclohexanol (trans, (1S,2R)-)
EINECS	Contact for details

Quality Control

Our (1S,2R)-(+)-trans-2-Phenyl-1-Cyclohexanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting specifications for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.