Description

S-(+)-Albuterol is the pharmacologically active enantiomer of the widely used bronchodilator albuterol (salbutamol). This high-purity chiral building block is essential for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced respiratory therapeutics. It is a critical raw material for pharmaceutical manufacturers and research institutions focused on pulmonary diseases, asthma, and COPD treatments.

Application

• Primary chiral intermediate for the synthesis of enantiopure Levalbuterol (R-albuterol) HCl API.
• Key starting material in advanced pharmaceutical research for next-generation bronchodilators and β-2 adrenergic agonists.
• Reference standard for analytical method development and quality control in pharmaceutical production.
• Used in preclinical and clinical studies investigating the specific effects of the S-enantiomer.
• Building block for novel drug conjugates and formulations targeting respiratory delivery systems.
• Intermediate in the synthesis of specialized metabolites for pharmacological studies.

Basic Information

Product Name	S-(+)-Albuterol
CAS No.	34271-50-6
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	(S)-(+)-Salbutamol; (S)-Albuterol; S(+)-Albuterol; (S)-4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; (S)-α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α'-diol; S-Albuterol Base; S-(+)-Salbutamol Free Base; (S)-AH-3365
EINECS	Contact for details

Quality Control

Our S-(+)-Albuterol is manufactured under strict quality management systems. It undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.