Description

(R)-3-Methyl-6,8-Dihydroxy-7-Methoxyisochroman-1-One is a high-purity, chiral isochromanone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of complex molecules, particularly in the pharmaceutical sector. It is essential for research and production teams in fine chemical, pharmaceutical R&D, and agrochemical industries seeking to incorporate its specific stereochemistry and functional groups into target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-infective drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex, enantiomerically pure molecular architectures.
• Natural Product Synthesis: Serves as a core structural motif or precursor in the total synthesis of natural products containing isochromanone or benzopyran scaffolds.
• Agrochemical Research: Investigated as an intermediate for developing new chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science Research: Potential precursor for synthesizing specialty polymers or organic electronic materials with specific optical properties.
• Biochemical Probe Development: Used in academic and industrial research to create molecular probes for studying enzyme mechanisms or biological pathways.

Basic Information

Product Name	(R)-3-Methyl-6,8-Dihydroxy-7-Methoxyisochroman-1-One
CAS No.	34223-77-3
Molecular Formula	C11H12O5
Molecular Weight	224.21 g/mol
Synonyms	(R)-3-Methyl-6,8-dihydroxy-7-methoxy-1H-isochromen-1-one; (R)-6,8-Dihydroxy-7-methoxy-3-methylisochroman-1-one; (R)-7-O-Methylalternariol; (R)-3-Methyl-6,8-dihydroxy-7-methoxyisochromanone; Alternariol 7-methyl ether (R-enantiomer); (R)-AOH-7-Me; (R)-3-Methyl-6,8-dihydroxy-7-methoxy-3,4-dihydro-1H-isochromen-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity fine chemicals. We provide comprehensive analytical data including chiral purity (enantiomeric excess) and chemical purity determined by advanced chromatographic methods. Certificates of Analysis (COA) are available upon request, detailing specifications for identity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.