Description

9-Oxo-11Alpha-15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic-3,3,4,4-D4 Acid is a deuterium-labeled analog of a key prostaglandin metabolite, offering a stable internal standard for precise analytical quantification. This high-purity compound is critical for ensuring accuracy and reliability in sensitive mass spectrometry and chromatography-based assays. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and advanced diagnostic developers for method validation and biomarker studies.

Application

• Internal Standard for LC-MS/MS: Essential for the accurate quantification of prostaglandins and related eicosanoids in complex biological matrices like plasma, urine, and tissue homogenates.
• Biomarker Research: Used in metabolic pathway studies and the development of diagnostic assays for inflammatory diseases, cardiovascular conditions, and reproductive health.
• Drug Metabolism and Pharmacokinetics (DMPK): Employed as a stable-isotope tracer to study the absorption, distribution, metabolism, and excretion (ADME) of prostaglandin-based therapeutics.
• Reference Standard: Serves as a certified reference material (CRM) for calibrating analytical instruments and validating testing methods in GLP/GMP environments.
• Academic Research: Facilitates fundamental studies in lipidomics, biochemistry, and molecular biology focused on the arachidonic acid cascade and its physiological roles.

Basic Information

Product Name	9-Oxo-11Alpha-15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic-3,3,4,4-D4 Acid
CAS No.	34210-10-1
Molecular Formula	C₂₀H₂₈D₄O₅
Molecular Weight	356.48 g/mol
Synonyms	11α,15S-Dihydroxy-9-oxoprosta-5Z,13E-dien-1-oic-3,3,4,4-d4 Acid; Deuterated PGD2 Metabolite; 9-Keto-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 Acid; 9-Oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 Acid; d4-9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic Acid; 3,3,4,4-d4-9-Oxo-11α,15S-dihydroxy-prosta-5Z,13E-dienoic Acid; 9-Oxo-11α,15S-dihydroxy-prosta-5Z,13E-dienoic-3,3,4,4-d4 Acid
EINECS	Contact for details

Quality Control

Every batch of 9-Oxo-11Alpha-15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic-3,3,4,4-D4 Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity, isotopic enrichment, and structural identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Isotopic Purity (d4)	≥ 98 atom % D
Chemical Purity	≥ 97%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.