Description

(14R)-2β,3β-Epoxygrayanotoxane-5,6β,7α,9,10,14,16-Heptaol 7-Acetate 14-Propionate CAS NO 34183-45-4 is a complex diterpenoid derivative belonging to the grayanotoxin family, characterized by its specific epoxy and ester functional groups. This compound is of significant interest for advanced research and development due to its intricate molecular architecture, which serves as a valuable scaffold for studying structure-activity relationships and synthesizing novel analogs. It is primarily sought by researchers in pharmaceutical discovery, natural product chemistry, and toxicology for use as a reference standard or a key synthetic intermediate.

Application

• Pharmaceutical Research & Development: As a high-purity reference standard for analytical method development, validation, and quality control in drug discovery pipelines.
• Natural Product Chemistry: Serving as a critical intermediate or target molecule for the total synthesis or semi-synthesis of complex grayanotoxin analogs.
• Toxicological Studies: Used in research to investigate the mechanisms of action, metabolic pathways, and biological effects of grayanotoxin-related compounds.
• Academic Research: A key material for universities and institutes conducting studies in organic synthesis, medicinal chemistry, and plant toxin biochemistry.
• Biochemical Assay Development: Employed as a precise reagent in the development of screening assays for ion channel modulation or other relevant biological targets.

Basic Information

Product Name	(14R)-2β,3β-Epoxygrayanotoxane-5,6β,7α,9,10,14,16-Heptaol 7-Acetate 14-Propionate
CAS No.	34183-45-4
Molecular Formula	C27H38O12
Molecular Weight	554.59 g/mol
Synonyms	Grayanotoxin XVIII 7-acetate 14-propionate; (14R)-2β,3β-Epoxygrayanotoxane-5,6β,7α,9,10,14,16-heptaol 7-acetate 14-propanoate; 14-Propionylgrayanotoxin XVIII 7-acetate; Grayanotoxin derivative 34183-45-4; 2β,3β-Epoxy-14-propionylgrayanotoxin XVIII 7-acetate; Acetylpropionylgrayanotoxin; 7-O-Acetyl-14-O-propionylgrayanotoxin XVIII
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.