Description

Methyl 7-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylate is a high-purity, functionalized benzothiophene derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific chlorinated and hydroxylated benzothiophene motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzothiophene core.
• Material Science Research: Serves as a precursor for developing organic semiconductors, liquid crystals, and other functional materials due to its conjugated thiophene system.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in heterocyclic chemistry and as a starting material for complex molecular libraries.
• Fine Chemical Production: Acts as an intermediate in the custom synthesis of specialty chemicals, dyes, and pigments.

Basic Information

Product Name	Methyl 7-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylate
CAS No.	33851-23-9
Molecular Formula	C10H7ClO3S
Molecular Weight	242.68 g/mol
Synonyms	Methyl 7-chloro-3-hydroxy-1-benzothiophene-2-carboxylate; 7-Chloro-3-hydroxybenzo[b]thiophene-2-carboxylic acid methyl ester; 2-Carbomethoxy-7-chloro-3-hydroxybenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 7-chloro-3-hydroxy-, methyl ester; Methyl 7-chloro-3-hydroxybenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 7-Chloro-3-Hydroxybenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.