Description

1-Aminoadamantane-D15 is a deuterated derivative of amantadine, where fifteen hydrogen atoms are replaced with the stable isotope deuterium. This high-purity labeled compound is essential for advanced research and development, providing a critical internal standard for precise quantitative analysis. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working in drug metabolism studies, pharmacokinetics, and the development of novel diagnostic methods.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical reference compound in LC-MS and GC-MS analysis for the accurate quantification of amantadine and related compounds in biological matrices.
• Pharmaceutical Research & Metabolite Tracing: Used in drug metabolism and pharmacokinetic (DMPK) studies to track and elucidate metabolic pathways without interference from endogenous compounds.
• Deuterated Building Block: Acts as a specialized synthon for the synthesis of more complex deuterated molecules for research in medicinal chemistry and material science.
• Analytical Method Development: Employed in the validation and calibration of analytical methods to ensure compliance with regulatory standards for accuracy and precision.
• Neuropharmacology Studies: Supports research into neurological pathways and the mechanism of action of adamantane-based therapeutics.

Basic Information

Product Name	1-Aminoadamantane-D15
CAS No.	33830-10-3
Molecular Formula	C10D15N
Molecular Weight	167.33 g/mol
Synonyms	Adamantan-1-amine-D15; Deuterated Amantadine (D15); 1-Adamantylamine-D15; 1-Aminotricyclo[3.3.1.13,7]decane-D15; Amantadine-D15; 1-Amantadine-D15; Perdeuterated 1-Aminoadamantane; Tricyclo[3.3.1.13,7]decan-1-amine-D15
EINECS	Contact for details

Quality Control

Every batch of 1-Aminoadamantane-D15 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation are available for each lot. Our quality protocols are designed to support compliance with relevant research and regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider sealing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.