Description

3-Chloro-2-Nitrothiophene is a versatile and high-value heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both chloro and nitro substituents on the thiophene ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and biological properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its bioactive thiophene core.
• Material Science Research: Serves as a building block for creating conjugated polymers and organic semiconductors used in electronic devices like OLEDs and sensors.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments due to the chromophoric nature of the nitro-thiophene system.
• Ligand and Catalyst Development: Utilized to create novel ligands for transition metal catalysts used in cross-coupling and other organic transformations.

Basic Information

Product Name	3-Chloro-2-Nitrothiophene
CAS No.	33786-78-6
Molecular Formula	C4H2ClNO2S
Molecular Weight	163.58 g/mol
Synonyms	3-Chloro-2-nitrothiophene; 2-Nitro-3-chlorothiophene; Thiophene, 3-chloro-2-nitro-; 3-Chlor-2-nitrothiophen; 3-Chloro-2-nitro-thiophene; 3-Chloro-2-nitrothiofene; 3-Cl-2-NO2-Thiophene
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Nitrothiophene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.