Description

5-[1-Hydroxy-2-[(1-Methyl-3-Phenylpropyl)Amino]Ethyl]Salicylic Acid Methyl Ester Hydrochloride is a high-purity organic salt compound, primarily valued as a key synthetic intermediate in advanced pharmaceutical research and development. Its complex molecular structure, featuring both salicylate and amino alcohol motifs, makes it a critical building block for creating novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug molecules, particularly those targeting cardiovascular or neurological pathways.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new chemical entities (NCEs) and lead compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the production of specific, proprietary APIs where its structural framework is integral to biological activity.
• Biochemical Research: Employed in studies investigating enzyme interactions or receptor binding mechanisms due to its specific pharmacophore.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science or agrochemical applications.

Basic Information

Product Name	5-[1-Hydroxy-2-[(1-Methyl-3-Phenylpropyl)Amino]Ethyl]Salicylic Acid Methyl Ester Hydrochloride
CAS No.	33778-93-7
Molecular Formula	C20H25NO4·HCl
Molecular Weight	379.88 g/mol
Synonyms	Salmetrol Intermediate; 5-[1-Hydroxy-2-[(1-Methyl-3-phenylpropyl)amino]ethyl]-2-hydroxybenzoic acid methyl ester hydrochloride; Methyl 5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]salicylate hydrochloride; Salmeterol Impurity; Salmeterol Related Compound; (RS)-Salmeterol Methyl Ester Hydrochloride; 2-Hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzoic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 5-[1-Hydroxy-2-[(1-Methyl-3-Phenylpropyl)Amino]Ethyl]Salicylic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.