Description

Benzyl-Alpha,α-D2 Chloride is a deuterated organic reagent where two hydrogen atoms at the alpha position are replaced with deuterium, a stable hydrogen isotope. This isotopic labeling is critical for mechanistic studies, metabolic pathway tracing, and the synthesis of deuterated pharmaceutical compounds, providing enhanced stability and distinct analytical signatures. It is an essential building block for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science who require precise isotopic purity for their applications.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing deuterated active pharmaceutical ingredients (APIs) with improved metabolic profiles.
• Mechanistic & Metabolic Studies: Used as a tracer in reaction mechanism elucidation and drug metabolism studies via Mass Spectrometry (MS) and NMR.
• Agrochemical Research: Synthesis of deuterated pesticides and herbicides for environmental fate and degradation studies.
• Organic Synthesis Reagent: Acts as a benzylating agent in reactions where deuterium labeling is required for spectroscopic analysis.
• Material Science: Used in the development of specialty polymers and liquid crystals with specific isotopic properties.
• Analytical Standard: Serves as an internal standard or reference material in quantitative analytical methods like LC-MS.

Basic Information

Product Name	Benzyl-Alpha,α-D2 Chloride
CAS No.	33712-34-4
Molecular Formula	C7H5D2Cl
Molecular Weight	128.60 g/mol
Synonyms	(Dideuteriochloromethyl)benzene; α,α-Dideuteriobenzyl Chloride; Benzyl-α,α-d2 Chloride; Benzyl Chloride-d2; (Chloromethyl-d2)benzene; Phenyl-D2-chloromethane; NSC 406913
EINECS	Contact for details

Quality Control

Every batch of Benzyl-Alpha,α-D2 Chloride is produced and tested under stringent quality management protocols. We guarantee high isotopic purity and chemical purity to meet the exacting requirements of research and development. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as isotopic enrichment (D atom%), chemical purity by GC/HPLC, and identity confirmation by NMR and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (D atom%)	≥ 98.0 atom% D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.