Description

5-(2-Chlorophenyl)-7-Ethyl-1,3-Dihydro-2H-Thieno[2,3-E]-1,4-Diazepin-2-One is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of novel therapeutic agents, particularly within the central nervous system (CNS) drug discovery pipeline. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new benzodiazepine and thienodiazepine analogs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel psychoactive compounds and potential anxiolytic or sedative-hypnotic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new drugs targeting GABA receptors.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Employed in pharmacological studies to investigate the mechanisms of benzodiazepine-site ligands.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value heterocyclic molecules.

Basic Information

Product Name	5-(2-Chlorophenyl)-7-Ethyl-1,3-Dihydro-2H-Thieno[2,3-E]-1,4-Diazepin-2-One
CAS No.	33671-37-3
Molecular Formula	C₁₅H₁₃ClN₂OS
Molecular Weight	304.79 g/mol
Synonyms	7-Ethyl-5-(2-chlorophenyl)-1,3-dihydro-2H-thieno[2,3-e][1,4]diazepin-2-one; 5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one; Thienodiazepinone derivative; 33671-37-3; 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e][1,4]diazepin-2-one
EINECS	Contact for details

Quality Control

Our 5-(2-Chlorophenyl)-7-Ethyl-1,3-Dihydro-2H-Thieno[2,3-E]-1,4-Diazepin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Any single impurity ≤1.0%; Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.