Description

(-)-Methylphenylphosphinic Acid Ethyl Ester is a chiral organophosphorus compound of significant interest in advanced chemical synthesis. This high-purity enantiomer serves as a crucial building block and chiral ligand or catalyst precursor in asymmetric catalysis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients. Its defined stereochemistry enables precise control over reaction pathways, making it essential for producing enantiomerically pure products.

Application

• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in transition metal-catalyzed reactions, such as hydrogenations and cross-couplings.
• Pharmaceutical Intermediates: A key precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or additive in the development of specialized polymers and advanced materials with tailored properties.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and catalysis studies.

Basic Information

Product Name	(-)-Methylphenylphosphinic Acid Ethyl Ester
CAS No.	33642-98-7
Molecular Formula	C9H13O2P
Molecular Weight	184.17 g/mol
Synonyms	Ethyl (-)-Methylphenylphosphinate; (R)-(-)-Ethyl Methylphenylphosphinate; (-)-Ethyl Methylphenylphosphinate; P-Methyl-P-phenylphosphinic Acid Ethyl Ester; Ethyl P-Methyl-P-phenylphosphinate; (R)-Ethyl Methylphenylphosphinate; L-(-)-Ethyl Methylphenylphosphinate; Methylphenylphosphinic Acid Ethyl Ester, (-)-
EINECS	Contact for details

Quality Control

Our (-)-Methylphenylphosphinic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by methods such as HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.