Description

2-(Fluoromethyl)-1H-Isoindole-1,3(2H)-Dione is a specialized fluorinated isoindole-1,3-dione derivative, a high-value building block in advanced organic synthesis. Its core value lies in the strategic introduction of a fluoromethyl group, enabling precise modulation of molecular properties for research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers developing novel active ingredients. It serves as a key intermediate in the creation of potential drug candidates and specialty chemicals requiring fluorinated motifs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the fluoromethyl group enhances bioavailability and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) and introducing fluorine atoms into complex molecular architectures in academic and industrial R&D.
• Ligand and Catalyst Development: Employed in the design of novel fluorinated ligands for catalytic systems and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(Fluoromethyl)-1H-Isoindole-1,3(2H)-Dione
CAS No.	33551-68-7
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	N-Fluoromethylphthalimide; 1H-Isoindole-1,3(2H)-dione, 2-(fluoromethyl)-; Fluoromethylphthalimide; 2-Fluoromethylphthalimide; N-(Fluoromethyl)phthalimide; Phthalimide, N-(fluoromethyl)-; 33551-68-7; N-Fluoromethyl-1,3-dihydro-2H-isoindole-1,3-dione
EINECS	Contact for details

Quality Control

Our 2-(Fluoromethyl)-1H-Isoindole-1,3(2H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.