Description

6-Chloro-1,2,3,4-Tetrahydroisoquinoline is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core structure serves as a privileged scaffold for constructing complex molecules with targeted biological activity. This intermediate is particularly valuable for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive molecules, including potential central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Chemical Research & Development: Serves as a fundamental building block for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials with specific functional properties.

Basic Information

Product Name	6-Chloro-1,2,3,4-Tetrahydroisoquinoline
CAS No.	33537-99-4
Molecular Formula	C9H10ClN
Molecular Weight	167.64 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydroisoquinoline; 6-Chloro-THIQ; 6-Chloro-3,4-dihydro-1H-isoquinoline; 6-Chloro-1,2,3,4-tetrahydro-isoquinoline; 6-Chloro-3,4-dihydroisoquinoline; 6-Chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride (salt form); 6-Cl-THIQ
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,2,3,4-Tetrahydroisoquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.