Description

Diethyl (Phthalimidomethyl)Phosphonate is a specialized organophosphorus compound that serves as a key synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a versatile reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient construction of complex alkenes and heterocyclic systems. This high-purity building block is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of complex drug candidates, particularly for constructing alkene linkages in molecules with potential therapeutic activity.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators that require specific alkene functionalities.
• Material Science Research: Employed in the creation of specialized polymers, liquid crystals, and organic electronic materials where precise molecular architecture is required.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and for preparing bespoke chemical libraries for screening.
• Peptidomimetic Chemistry: Facilitates the introduction of phosphonate and alkene groups into peptide analogs to modify stability and biological activity.

Basic Information

Product Name	Diethyl (Phthalimidomethyl)Phosphonate
CAS No.	33512-26-4
Molecular Formula	C14H18NO5P
Molecular Weight	311.27 g/mol
Synonyms	Diethyl (Phthalimidomethyl)Phosphonate; Diethyl (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-ylmethyl)phosphonate; (Phthalimidomethyl)phosphonic Acid Diethyl Ester; Diethyl P-(Phthalimidomethyl)phosphonate; NSC 334983; Phosphonic acid, P-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl (Phthalimidomethyl)Phosphonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.