Description

(3-Phenoxy-2-Oxopropylidene)Triphenylphosphorane is a specialized Wittig reagent, a key organophosphorus compound used in synthetic organic chemistry. Its primary value lies in its ability to facilitate the stereoselective synthesis of alkenes, particularly α,β-unsaturated carbonyl compounds, which are crucial intermediates in fine chemical and pharmaceutical manufacturing. This high-purity reagent is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and efficient olefination reactions.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing complex molecular frameworks, particularly in the synthesis of drug candidates containing α,β-unsaturated ester or ketone functionalities.
• Agrochemical Production: Used in the synthesis of active ingredients and advanced intermediates for crop protection agents, leveraging its precise olefination capabilities.
• Fine Chemical Manufacturing: Enables the production of specialty chemicals, flavors, fragrances, and advanced monomers where controlled alkene formation is required.
• Academic & Industrial R&D: Serves as a fundamental tool in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Material Science Precursors: Applicable in the synthesis of organic ligands and molecular building blocks for advanced polymers and functional materials.

Basic Information

Item	Details
Product Name	(3-Phenoxy-2-Oxopropylidene)Triphenylphosphorane
CAS No.	33502-03-3
Molecular Formula	C27H23O2P
Molecular Weight	410.45 g/mol
Synonyms	(Carbethoxymethylene)triphenylphosphorane (Phenoxy analog); 3-Phenoxy-2-oxopropylidenetriphenylphosphorane; Ethyl (triphenylphosphoranylidene)phenoxyacetate; Phenoxy(triphenylphosphoranylidene)acetate; Wittig reagent phenoxy variant; (Phenoxycarbonylmethylene)triphenylphosphorane; Triphenyl(phenoxycarbonylmethylene)phosphorane
EINECS	Contact for details

Quality Control

Our production of (3-Phenoxy-2-Oxopropylidene)Triphenylphosphorane adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ³¹P), HPLC for purity assessment, and melting point determination to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to maximize stability and shelf-life. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.