Description

Calcium Dipropylacetate Hydrate is the calcium salt of dipropylacetic acid, commonly known as valproic acid, in a hydrated form. This compound is a critical pharmaceutical intermediate, primarily valued for its role in synthesizing active pharmaceutical ingredients (APIs) for anticonvulsant and mood-stabilizing medications. It is essential for manufacturers in the pharmaceutical and fine chemical sectors requiring high-purity raw materials for regulated drug production.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of valproic acid and its derivatives, which are used in antiepileptic and bipolar disorder treatments.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the production of finished dosage forms such as tablets, capsules, and extended-release formulations.
• Research & Development: Used in preclinical and clinical research for developing new central nervous system (CNS) therapeutics.
• Chemical Reference Standard: Serves as a high-purity standard for analytical testing and quality control in pharmaceutical laboratories.
• Fine Chemical Synthesis: Utilized as a building block for other specialty organic compounds requiring the dipropylacetate moiety.

Basic Information

Product Name	Calcium Dipropylacetate Hydrate
CAS No.	33433-82-8
Molecular Formula	C10H18CaO4 • xH2O
Molecular Weight	Anhydrous: 242.33 g/mol (Contact for exact hydrate weight)
Synonyms	Calcium Valproate Hydrate; Calcium Dipropylacetate; Valproic Acid Calcium Salt; Calcium 2-Propylpentanoate; Calcium 2-Propylvalerate; Dipropylacetic Acid Calcium Salt; Calcium Divalproex (related compound); Calcium 2-Propylpentanoate Monohydrate
EINECS	Contact for details

Quality Control

Our Calcium Dipropylacetate Hydrate is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing parameters such as assay, impurity profile, and residual solvents. We can support compliance with ICH Q7 guidelines and other relevant pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	As per COA (Hydrate form)
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.