Description

L-Chlorprenaline Hydrochloride is a high-purity chiral compound of significant interest in advanced pharmaceutical synthesis. Its primary value lies in its role as a key synthetic intermediate for the development of active pharmaceutical ingredients (APIs), particularly those targeting adrenergic pathways. This product is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors requiring precise, high-quality building blocks for drug discovery and development.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of β-2 adrenergic receptor agonists and related therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the research and production of novel bronchodilators and other cardiovascular or respiratory medications.
• Biochemical Research: Serves as a standard or reagent in pharmacological studies investigating adrenergic system mechanisms.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined L-configuration, enabling the production of enantiomerically pure compounds.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for method development and quality control.

Basic Information

Product Name	L-Chlorprenaline Hydrochloride
CAS No.	33404-82-9
Molecular Formula	C9H13Cl2NO
Molecular Weight	222.11 g/mol
Synonyms	(1R,2S)-1-(3,4-Dichlorophenyl)-2-amino-1-propanol hydrochloride; (-)-Chlorprenaline HCl; L-(-)-Chlorprenaline hydrochloride; (1R,2S)-Chlorprenaline hydrochloride; (R*,S*)-1-(3,4-Dichlorophenyl)-2-aminopropan-1-ol hydrochloride; 2-Amino-1-(3,4-dichlorophenyl)-1-propanol hydrochloride (L-form); Clorprenaline hydrochloride (L-isomer)
EINECS	Contact for details

Quality Control

Our L-Chlorprenaline Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced chromatographic methods (HPLC, GC). We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation [α]	Contact for details
Related Substances (HPLC)	Total impurities ≤1.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.